Astrocytes are the major glial cell in the central nervous system. These polarized cells elaborate numerous processes that ensheath the vasculature and contact synapses. Astrocytes play important ...

"When we looked at gene expression, we saw that a number of processes were altered in the resilient group. First of all, the astrocytes appeared to produce more of the antioxidant metallothionein.

Zhang next combined single cell sequencing with lineage tracing to molecularly characterize all of the converted astrocytes’ progeny and illuminate the reprogramming process. “We used a bioinformatic ...

Therefore, in this study, the researchers primarily focused on validating several functional assays designed to assess vital biological processes that astrocytes are involved in and could ...

They conducted a genetic analysis on astrocytes of mice with glioblastoma tumors and those without, and noticed an increase in the expression levels of genes that disrupted metabolic processes in the ...

Understanding these mechanisms could shed light on processes that are still poorly understood, such as the brain's spontaneous repair after injury. The presence of proliferative astrocytes in white ...

Get Instant Summarized Text (Gist) The study identifies distinct subtypes of white matter astrocytes, including a unique type with regenerative potential. Using advanced sequencing techniques ...