Number of tacrolimus dose modifications until stable tacrolimus therapeutic trough concentrations were achieved 19 ± 9 15 ± 9 0.007 All results are expressed as mean ± standard deviations ...
Patients were self-assigned to at least 24 weeks of oral tacrolimus (n = 12; target trough level 4–8 ng/ml) or intravenous ciclosporin (n = 14; 750 mg/m 2 body surface area once every 4 weeks).
In the present study, donor CYP3A5 genotype was found to be strongly associated with the time to reach stable tacrolimus therapeutic trough concentrations and tacrolimus daily dose requirements in ...
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