DNA methylation refers to the process of adding a methyl group to specific regions of DNA. This process can bring about changes in the activity of DNA without changing the sequence of nucleotides.

During DNA replication, the unwinding of strands leaves a single strand vulnerable. How does the cell protect these strands from damage? How would you identify the protein that serves as a connector ...

Replication fork reversal is a complex transaction that requires the coordinated unwinding and annealing of parental and newly synthesized strands at the replication fork. Replication fork reversal is ...

The segregation of plasmid DNA typically requires three elements: a DNA centromere site, an NTPase, and a centromere-binding protein. Because of their simplicity, plasmid partition systems represent ...

Scientists have successfully described a crucial structure involved in DNA replication, placing another piece in the puzzle of how life propagates. Scientists at Van Andel Research Institute and ...

Replication protein A (RPA), a highly conserved single-stranded DNA-binding protein in eukaryotes, is a stable complex comprising three subunits termed RPA1, RPA2, and RPA3. RPA is required for ...