Scientists at the Faculty of Medicine have now developed an innovative numbering system for the GAIN domain, a protein domain common to all adhesion GPCRs. It should help to elucidate the role of ...

Using the CRISPR/Cas9 genome-editing system to mutate the gene regions encoding particular protein domains could result in a new and more efficient method to screen for druggable protein targets ...

Each cell in your body relies on precise communication with other cells to function properly. At the center of this process ...

This is the metadata section. Skip to content viewer section. J-domain proteins (JDPs) are the largest family of chaperones in most organisms, but much of how they function within the network of other ...

In the inactive conformation, the a-subunit of the G protein binds to GDP and is bound to a beta-gamma complex (a). Upon receptor activation by its ligand, there is an exchange of GDP for GTP (b).