Generations of students have been introduced to this subject with the first and second editions of Enzyme structure and mechanism ... of protein engineering and its effects on folding and activity.

Usually a protein is capable of finding its functional or native state ... Under normal circumstances, the cell has mechanisms to prevent proteins from folding incorrectly, as well as to get ...

This implicates co-translational folding as a crucial mechanism that facilitates ... the ribosome is both essential to life in its facilitation of protein folding but can also be involved in ...

The researchers tested their method on the protein adenylate kinase and found that its predicted movements ... landscape that otherwise guides the folding, called local frustration, are essential ...