Three-D Images Shed Light On First Steps Of RNA Synthesis Date: May 17, 2002 Source: Rockefeller University Summary: The first three-dimensional images of the initiating form of the molecular ...

More information: Chauvier, A. et al, Structural basis for control of bacterial RNA polymerase pausing by a riboswitch and its ligand, Nature Structural & Molecular Biology (2023).

New study shows RNA polymerase I halts at abasic DNA damage, helping prevent faulty rRNA production and exposing lesions for ...

The coronavirus that causes COVID-19, SARS-CoV-2, is known as a positive-strand RNA virus because of the way it stores and makes copies of its genetic material. Many other important pathogens such as ...

The big RNA picture. ... FISSEQ debuted in 2003, based on generating polymerase colonies of copied DNA molecules on a glass slide coated with polyacrylamide matrix.

Capturing the Viral Copy Machine. The team used advanced electron microscopy to capture thousands of individual images of the ...

Role of RNA polymerase in gene transcription demonstrated Date: July 19, 2010 Source: University of Maryland Summary: Biophysicists have provided new insight into the mechanisms of gene transcription.

Under the influence of transcription promoter regions, RNA polymerase jumps on DNA at the start sites and gets off at the end of genes. However tidy that view seems, a quartet of papers in today’s ...

In addition to its newly launched CleanScribe RNA Polymerase, TriLink offers mRNA capping analogs (including the award-winning CleanCap® M6), mRNA raw materials (nucleotides and other IVT enzymes ...

These results indicate that the RNA polymerase of SARS-CoV-2 utilizes electrostatic interaction to take up the nucleotides such as ATP and the drugs such as remdesivir and favipiravir.