Figure 2: Electron density maps of the 30S, 50S and 70S ribosomal particles. Although high quality diffracting crystals of the ribosome have been available for a number of years 5,6, the technical ...
Chloroplast ribosomes, which originated from cyanobacteria, comprise a large subunit (50S) and a small subunit (30S) containing ribosomal RNAs (rRNAs) and various ribosomal proteins. Genes for many ...
As the cell's protein factory, the ribosome is the only natural machine that manufactures its own parts. That is why understanding how the machine, itself, is made, could unlock the door to everything ...
At the end of the 1970s, Ada Yonath decided she was going to generate crystal structures of the ribosome using x-ray crystallography to establish the exact location of every atom -- considered an ...
Maturation of the ribosome is a complex operation. Work now shows that the 90S precursor of the small 40S subunit undergoes a 'molting' process, during which it progressively discards its outermost ...
One year later, in these Hot Papers, Ramakrishnan's group described the complete structure of the 30S subunit at 3 Angstrom resolution, both isolated and complexed with antibiotics. This information ...
The discovery of ribosomes dates back to the 1950s, when George Palade first observed dense particles in the cytoplasm of cells using electron microscopy. These particles were later named "ribosomes" ...
Evidence of human construction work is all around us: on the roads we travel, in the buildings we occupy and now even in outer space. But one form of “human construction” quietly does its job without ...
As the cell's protein factory, the ribosome is the only natural machine that manufactures its own parts. That is why understanding how the machine, itself, is made, could unlock the door to everything ...
Proteins are absolutely essential for the survival of organisms; they carry out many functions that are critical to life. Something needs to build all of those proteins from their basic components.