The Arizona Cardinals play the San Francisco 49ers in a game on the NFL Week 3 schedule on Sunday, Sept. 21, at the 49ers' Levi's Stadium in Santa Clara, California. Here's a look at the time,

Saints quarterback Spencer Rattler threw three touchdown passes himself and, for the second week in a row, had a chance to lead a game-winning drive. But the 49ers defense held, sacking Rattler on a fourth-and-1 to seal the win.

It was dicey for San Francisco's defense, but it was Huff flying off the edge on fourth-and-2 who got home and knocked the ball away from QB Spencer Rattler for his first sack of the season. His sack also ensured the 49ers took home a victory and moved to 2-0 on the season.

Brock Purdy missed the 49ers' win at the Saints on Sept. 14. The Arizona high school football standout could return vs. the Arizona Cardinals.

According to star 49ers defensive end Nick Bosa, there is one big reason why this season feels much better on the defensive side of the ball. The post Biggest Change Fueling San Francisco 49ers’ Defensive Success Revealed appeared first on Heavy Sports.

The Athletic's Dianna Russini shared an interesting quote from one NFL executive in a recent article. Russini reported that the anonymous front-office executive seriously dissed t

Kyle Juszczyk is a pro NFL player, but his wife Kristin Juszczyk is making a name for herself in the sport. After finding her niche in creating custom game day outfits for NFL fans — as well as the wives and girlfriends of athletes, including Taylor Swift and Brittany Mahomes — Kristin launched her own brand, Off Season, in January 2025.

Mac Jones kept it real when discussing his relationship with his new 49ers' teammate Bryce Huff after their prior run-ins.