The San Francisco 49ers are preparing for their Week 5 matchup against the Arizona Cardinals under challenging weather ...

The San Francisco 49ers were thought to be among the favorites to represent the NFC in the Super Bowl for a second straight year, but they haven't ...

Why San Francisco 49ers changed their uniform for NFL Week 5 game against Arizona Cardinals Sunday, and why it's not the ...

The San Francisco 49ers will wear alternate throwback uniforms that feature white pants to prepare for projected record-breaking temperatures during ...

Anyone trekking from Sacramento to the Bay Area on Sunday to watch the San Francisco 49ers would be ... In anticipation of the heat, the 49ers sought a wardrobe change, but the NFL this week denied ...

The record-breaking heat for a San Francisco 49ers game at Levi’s Stadium has sent fans at the game down to the concourses.

SportsLine's model simulated Arizona Cardinals vs. San Francisco 49ers 10,000 times and made its Week 5 NFL picks, ...

NFL Network's Sara Walsh explains why she believes the Baltimore Ravens are the team that would be the best landing spot for wide receiver Davante Adams if he does happen to be traded elsewhere by ...

Two weeks after faltering on the road to the Los Angeles Rams, the 49ers blew another 10-point lead and exited with a 24-23 ...

The 49ers ramped up McCaffrey’s rehab work this week, and Schefter reports that the team has “mild encouragement” that ... McBride has 14 catches for 122 yards so far this season. On Sunday in San ...

San Francisco 49ers running back Christaian McCaffrey will not play in the team's week two match up against the Minnesota Vikings. San Francisco 49ers running back Christian McCaffrey was active ...