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Acid phosphatase, Alkaline phosphatase, Protein tyrosine phosphatase, Serine/threonine phosphatase Phosphatase Inhibitor Cocktail III (-)-p-Bromotetramisole oxalate, Cantharidin, Calyculin A ...
Nakamura et al. 18 reported that the serine/threonine protein phosphatase inhibitor calyculin A enhanced cell killing when cells were treated 30 min before X-ray irradiation.
These phosphorylation events are detected using fluorescently-labeled anti-phospho-tryosine or anti-phospho-serine/threonine antibodies in real time with kinetic evaluation. Cell lysates are prepared ...
Deciphera Pharmaceuticals LLC has patented new serine/threonine-protein kinase B-raf (BRAF) and/or RAF proto-oncogene serine/threonine-protein kinase (RAF1; c-Raf) inhibitors reported to be useful for ...
Okadaic acid is a potent inhibitor of serine–threonine phosphatase subclasses PP2A, PP1, and PP2B. (PP stands for protein phosphatase.) It is the inhibition of this enzyme that is a primary cause of ...
Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) functions as a key regulator in inflammation and cell death and is involved in mediating a variety of inflammatory or degenerative ...
For patients with metastatic melanoma with activating mutations in serine-threonine protein kinase B-RAF (BRAF), treatment with the oral selective MEK inhibitor trametinib is associated with ...
The deal covers BI 860585, a phase II-ready potent and selective ATP-competitive mTOR serine/threonine kinase inhibitor. BI 860585 has already gone through a phase I trial of 90 patients with advanced ...
Oric Pharmaceuticals Inc. has described serine/threonine-protein kinase PLK4 (STK18) inhibitors reported to be useful for the treatment of cancer.
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