As a Black man, I knew about sickle cell all too well. The genetic disease that predominantly affects African and Caribbean people – rendering their blood cells sickle-shaped, leading to ...

But, as Krithika Varagur reports, love doesn’t always accord with the Punnett square. Providing a snapshot of what our “genetic responsibility” could be as prenatal tests proliferate, Varagur sat down ...

A Mississippi woman's life has been transformed by a treatment for sickle cell disease with the gene-editing technique CRISPR. All her symptoms from a disease once thought incurable have disappeared.

The US Food and Drug Administration on Friday approved two gene-based treatments for sickle cell disease, including the first therapy that uses the gene-editing technique CRISPR, opening a new era ...

Sickle-cell is caused by inheriting two bad copies of one of the genes that make hemoglobin. Symptoms include bouts of intense pain, and life expectancy with the disease is just 53 years.

The agency approved the treatment for patients with sickle cell disease and thalassemia who are 12 years old and over. Casgevy is made by Vertex Pharmaceuticals (Europe) Ltd. and CRISPR Therapeutics.

Those with sickle cell disease in the United States can have a shortened lifespan into their 50s, and even shorter in other countries. Roughly 100,000 Americans currently suffer from sickle cell ...

About 100,000 people in the United States have sickle cell disease. For the 20,000 or so with the most severe disease, gene therapy may be their only hope of living a normal life.