Sickle cell disease affects millions of people worldwide, but disproportionately those of African descent. Experts aren't sure exactly why people of African descent are more likely to inherit the ...

As a Black man, I knew about sickle cell all too well. The genetic disease that predominantly affects African and Caribbean people – rendering their blood cells sickle-shaped, leading to ...

But, as Krithika Varagur reports, love doesn’t always accord with the Punnett square. Providing a snapshot of what our “genetic responsibility” could be as prenatal tests proliferate, Varagur sat down ...

A Mississippi woman's life has been transformed by a treatment for sickle cell disease with the gene-editing technique CRISPR. All her symptoms from a disease once thought incurable have disappeared.

Sickle-cell disease is caused by a genetic mutation that leads to the production of Sickle hemoglobin, which affects the function of the red blood cells (RBCs) in the body.

The US Food and Drug Administration on Friday approved two gene-based treatments for sickle cell disease, including the first therapy that uses the gene-editing technique CRISPR, opening a new era ...

Sickle-cell is caused by inheriting two bad copies of one of the genes that make hemoglobin. Symptoms include bouts of intense pain, and life expectancy with the disease is just 53 years.

The US Food and Drug Administration has approved a second use for the first CRISPR-based medicine, Casgevy, which was approved in December to treat sickle cell disease.

The agency approved the treatment for patients with sickle cell disease and thalassemia who are 12 years old and over. Casgevy is made by Vertex Pharmaceuticals (Europe) Ltd. and CRISPR Therapeutics.