Single-stranded DNA-binding proteins (SSBs) are central guardians of genome integrity, selectively coating exposed single-stranded DNA (ssDNA) intermediates that arise during replication, ...
A few years ago, the advent of technology known as CRISPR was a major breakthrough in the scientific world. Developed from a derivative of the immune system of bacteria, CRISPR enables double strands ...
An INRS team discovers a new family of enzymes capable of inducing targeted cuts in single-stranded DNA . A few years ago, the advent of technology known as CRISPR was a major breakthrough in the ...
To assemble these minuscule structures, researchers first create a scaffold: a long piece of single-stranded DNA with a carefully designed sequence of bases. Then they add hundreds of shorter DNA ...
Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases. (Image: Wikimedia Commons, CC SA 3.0) The most common type of base pairing is the Watson-Crick base ...
For decades, scientists have largely relied on painstaking trial and error to coax proteins into crystalline forms. Crystallization enables scientists ...