Recent evidence suggests that natural products are much more than simply agents of “microbial warfare” and actually play critical roles in bacterial pathogenesis and communication. In particular, ...

The new method centres on the principle of enzyme inhibition. Countless pharmaceuticals, ranging from antibiotics to chemotherapy drugs, work by blocking the action of enzymes, and the search for new ...

Researchers have found a small molecule enzyme inhibitor capable of manipulating an immune process that plays an important role in cancers and autoimmune diseases. Researchers at the University of ...

In a new study published in Science Signaling titled, “Restoration of striatal neuroprotective pathways by kinase inhibitor treatment of Parkinson’s linked-LRRK2 mutant mice,” researchers from ...

Enzymes are biological catalysts that speed up chemical reactions in living organisms. They are essential for life, as they play a crucial role in various biological processes, such as digestion, ...

Fully automated pipeline allows for 500.000 binding energy predictions per month to speed up in silico enzyme and inhibitor screening and discovery projects GELEEN, NETHERLANDS, October 31, 2024 / ...

An international study led by scientists at Flinders University and at South China University of Technology has uncovered a new vulnerability in prostate cancer cells that could help improve treatment ...

A research team led by Dr Martin Mollenhauer from the Heart Center at University Hospital Cologne has investigated the link between obesity and the risk of cardiovascular disease in greater detail.