The approval was based on data from a phase 3 study which included adults with steroid-resistant active PMR who flared on at least 7.5mg per day of prednisone or equivalent during taper. The Food and ...
Autoimmune diseases (AD) such as rheumatoid arthritis, polymyalgia rheumatica, autoimmune thyroid disease and psoriasis, are a leading cause of morbidity and mortality as people age. Few effective ...
More than half of patients with polymyalgia rheumatica have a relapse during tapering of glucocorticoid therapy. Previous studies have suggested that interleukin-6 blockade may be clinically useful in ...
Findings showed secukinumab demonstrated statistically significant and clinically meaningful sustained remission at week 52 vs placebo. Topline data were announced from a phase 3 trial evaluating ...
After a brief appearance in the pandemic fight, Regeneron and Sanofi’s Kevzara is back with a new indication. Late Tuesday, the partners said the drug scored an FDA approval to treat polymyalgia ...
In patients with relapsing polymyalgia rheumatica, sarilumab with a rapid glucocorticoid taper regimen of 14 weeks led to greater improvements in patient-reported outcomes of health-related quality of ...
Please provide your email address to receive an email when new articles are posted on . Patients were more likely to achieve sustained remission with sarilumab vs. placebo. The most common adverse ...
Are you struggling with persistent pain and stiffness in your shoulders, neck or hips beyond the usual aches and pains of aging? Polymyalgia rheumatica, a common inflammatory rheumatic disease ...
BARCELONA, Spain — Compared with placebo, adding methotrexate (MTX) to treatment for newly diagnosed polymyalgia rheumatica (PMR) nearly doubled glucocorticoid (GC)-free remission rates at 1 year, ...
An arthritis drug may allow people to reduce use of steroids. * THE QUESTION Steroids are the treatment of choice for the widespread muscle pain and stiffness associated with the inflammatory disorder ...