Efficient T-cell engineering is crucial for the success of CAR T-cell therapy research, but it requires multiple labor-intensive steps, including T-cell isolation, activation, and transduction.

Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system. St. Jude Children's Research Hospital scientists recently ...

Renier Brentjens, MD, PhD, one of the pioneers in the development of chimeric antigen receptor (CAR) T-cell therapy, is poised to see the technology take its next big leap, with researchers testing ...

IB [email protected] of Chicago School of Medicine achieves first-ever automated 3-in-1 TCR-T manufacturing on Terumo Blood and Cell Technologies Quantum Flex Bioreactor ...

This academic-industry partnership reflects the need for a multidisciplinary approach to innovation in cell and gene therapy manufacturing.