Diastolic dysfunction refers to a cardiac condition caused by a “stiffening” of the heart’s ventricles, which restricts the heart’s ability to fill up with blood in between beats. Diastolic heart ...

Hypertension is believed to be the single greatest factor influencing the development of heart failure, particularly heart failure with preserved ejection fraction, also known as diastolic heart ...

Several observations from preclinical and short-term clinical studies support a role for sildenafil in the treatment of heart failure patients. The following discussion briefly considers each of these ...

VS-041 is currently being evaluated in a phase 1c trial in adult patients with heart failure with preserved ejection fraction and elevated serum levels of endotrophin. The Food and Drug Administration ...

Please provide your email address to receive an email when new articles are posted on . One in four women will develop heart failure with a higher prevalence of preserved vs. reduced ejection fraction ...

Two new studies on diastolic heart failure are starting at the German Centre for Cardiovascular Research (DZHK). They will investigate whether this form of heart failure can be better diagnosed and ...

Tatsuya Yoshida, Mikito Takefuji, and Toyoaki Murohara in the Department of Cardiology, Nagoya University Graduate School of Medicine, identified an enzyme, alpha-kinase 2 (ALPK2) that is specifically ...

The SGLT2 inhibitor medicines have changed how heart failure is managed. Originally sodium-glucose cotransporter 2 (SGLT2) inhibitors were used to lower blood sugar levels in people who have type 2 ...