In hepatocytes, bile acids are secreted into bile canaliculi by bile salt export pump (BSEP), cholesterol is secreted by ATP binding cassette subfamily G member 5 (ABCG5) and ABCG8 heterodimer and ...

For years, statins have been a mainstay of treatment for lowering cholesterol and reducing the risk of complications of heart disease. But, while they’re effective, they can come with intense side ...

Bacteria naturally present in the human intestine (known as the gut microbiota) can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking ...

More than a quarter of Americans over 40 take medications to lower their cholesterol, most of them statins. But not everyone can tolerate statins or wants to. Now a new study confirms that bempedoic ...

Bile acid is a liquid substance your liver produces to aid in food digestion. Your body usually releases bile at the correct levels based on the food you eat. But sometimes your body produces too much ...

Bile is a digestive fluid produced by the liver to help in the digestion of fat and absorption of nutrients. However, if you experience reflux (the flow of stomach contents into the esophagus), you ...