In hepatocytes, bile acids are secreted into bile canaliculi by bile salt export pump (BSEP), cholesterol is secreted by ATP binding cassette subfamily G member 5 (ABCG5) and ABCG8 heterodimer and ...
(A) The classic bile acid synthesis pathway: cholesterol 7α-hydroxylase (CYP7A1) converts cholesterol to 7α-hydroxycholesterol (7α-HOC). The sterol 12α-hydroxylase (CYP8B1) converts the intermediate ...
Bacteria naturally present in the human intestine (known as the gut microbiota) can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking ...
Bile acid is a liquid substance your liver produces to aid in food digestion. Your body usually releases bile at the correct levels based on the food you eat. But sometimes your body produces too much ...
8don MSN
Microbially produced secondary bile acids accelerate colorectal cancer development, study shows
For the first time, a team of experts from the Technical University of Munich (TUM), RWTH Aachen University, and the German ...
DEAR DR. ROACH: I’m a 67-year-old female in pretty good health. The only medications I take are for my thyroid, arthritis and hormone replacement. Early last year, I was sick with a cold/flu for a ...
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