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Mitochondrial pyruvate carrier structure solved after fifty yearsScientists at the Medical Research Council (MRC) Mitochondrial Biology Unit, University of Cambridge, have worked out the ...
Pyruvate and related metabolites are linked to reduced glaucoma risk among genetically predisposed individuals and mitigate disease in a mouse model, highlighting a potential metabolic mechanism of ...
The researchers identified the structure of this machine, the mitochondrial pyruvate carrier (MPC), and 50 years since its discovery, have shown how it operates like the lock on a canal to transport ...
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