How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...

Nucleic acid-based therapeutics, including antisense oligonucleotides (ASO), small interfering RNA (siRNA), messenger RNA (mRNA), immunomodulatory DNA/RNA, and gene-editing guide RNA (gRNA), hold ...

In the fast-evolving field of medical science, a new artificial intelligence model may be about to change the way mRNA-based drugs and vaccines are designed. Developed through a collaboration between ...

Messenger RNAs (mRNAs) possess unique properties making them great therapeutic candidates. However, delivering mRNA drugs to target cells is challenging. Protein nanocages (PNCs) are nanostructures ...

This is a preview. Log in through your library . Abstract Loss of the fragile X mental retardation protein (FMRP) causes fragile X syndrome (FXS). FMRP is widely thought to repress protein synthesis, ...

In recent years, messenger RNA (mRNA) has emerged as a promising avenue for accurate and potent therapeutic interventions. Unlike DNA drugs, mRNA can express genetic information without the risk of ...