This study presents important findings for the understanding of central brain circuits that underlie nociception-induced escape. Using a laser-based nociception assay, chronic neuronal silencing, ...

In a recent study published in Nature Neuroscience, a group of researchers explored how the cerebellum directly affects dopamine release in the substantia nigra compacta (SNc). While the cerebellum's ...

Parkinson’s disease (PD) is entering a pivotal phase. For decades, treatment has centred on dopamine replacement to manage ...

While there are several thousand drugs available to treat a wide range of brain diseases, from depression to schizophrenia, they cannot penetrate the blood-brain barrier (BBB) into the brain. The BBB, ...

This diagram shows that dopamine regulates neuron specification, suggesting its role in modulating neural circuits during development, potentially contributing to autism spectrum disorder–related ...

Drug addiction poses a global public health challenge, with limited therapeutic options and modest efficacy. While clinical observations suggest that social rank plays a crucial role in determining ...