Curative-intent multimodality treatment—combining local treatments such as surgery or radiotherapy with systemic therapy—is ...

Background The long-acting monoclonal antibody nirsevimab and respiratory syncytial virus (RSV) vaccines became available for prevention of severe RSV-associated disease in 2023. While clinical trials ...

Introduction Breathlessness is a common cause of hospital admission globally and is associated with high mortality, ...

A common eligibility criterion in respiratory clinical trials is a per cent-predicted forced expiratory volume in 1 second ...

Introduction Paternal prepubertal passive smoke exposure may increase the risk of childhood asthma. However, its association with impaired lung function trajectories at risk of chronic obstructive ...

Background Hospitalisation due to acute exacerbations of COPD (AECOPD) is common, and subsequent mortality high. The DECAF score was derived for accurate prediction of mortality and risk ...

Platypnoea–orthodeoxia syndrome (POS) is a rare disorder, manifesting as deoxygenation occurring when the patient is in the upright position. Four broad mechanisms for the condition have been ...

Background Previous studies have reported an association between warm temperature and asthma hospitalisation. They have reported different sex-related and age-related vulnerabilities; nevertheless, ...

Correspondence to Sosse E Klarenbeek, Department of Medical Imaging, Radboudumc, Nijmegen 6500 HB, Gelderland, The Netherlands; sosse.klarenbeek{at}radboudumc.nl Background The assumption that more ...

Background: Quadriceps weakness and loss of muscle mass predict mortality in chronic obstructive pulmonary disease (COPD). It was hypothesised that a reduced quadriceps cross-sectional area could be ...

Background: Muscle wasting and decreased muscle oxidative capacity commonly occur in patients with chronic obstructive pulmonary disease (COPD). Polyunsaturated fatty acids (PUFA) have been shown to ...

Academic Unit of Respiratory Medicine, St Bartholomew’s and Royal London School of Medicine and Dentistry, London EC1A 7BE, UK Correspondence to: Professor J A Wedzicha, Academic Unit of Respiratory ...