A mutation causes a defect in the production of exosomes, which has been shown to drive the progression of Alzheimer's ...

Results reported in a preprint connect localized signals in the brain to aging-related changes in immune cells in mouse ...

Next-generation sequencing enhances a biologics manufacturer's ability to detect and identify unknown or unexpected contaminants.

Impurities and instability are challenges for all drugs, but a growing range of technological tools are helping drug developers and manufacturers minimize them.

GEN spotlights some of the remarkable women who are breaking barriers, setting standards, and driving innovation in this space.

The method offers a scalable way to scour unculturable bacteria for new drug leads and help illuminate a previously hidden microbial world.

Discovering ways to regulate the BNST brain center may lead to new therapies for weight control and chemotherapy side effects.

Researchers engineered and screened dozens of base editors to precisely target a single mutation without editing other portions of the DNA.

Phage tail piracy is a cross-species gene-transfer path that spreads AMR and creates new targets for antimicrobial therapies.

An immunotherapy drug candidate safely prevents cancer cells from hiding from the immune system’s first responders.

ApoD may represent a target for therapeutic intervention designed to protect against severe influenza virus infection in ...

A novel decoy mechanism targets the once therapeutically elusive STAT3 transcription factor and mitigates cat oral cancer in ...