A marathon Sunday of Week 5 produced plenty of winners and losers, with the 49ers and Bills among the teams sparking concerns ...

This is the live blog for the San Francisco 49ers' Week 5 home game against the Arizona Cardinals. I will update this frequently with information ...

The NFL certainly didn't disappoint in Week 5, one of the wildest weeks in the young year. Five games featured the ...

Two members of Pittsburgh's dominant "Steel Curtain" defense from the 1970s have advanced to the next stage in voting for the ...

The Dallas Texans, first pro football team in the Southwest, proved their season opening defeat was no fluke by losing 37-14 to the San Francisco 49’ers on Oct. 5, 1952.

New Orleans & Atlanta both looking to bounce back from a Week 3 home loss. Will Derek Carr and the Saints offense get back on ...

This season, the scheduling Gods worked in San Francisco’s favor as they host the rebuilding New England Patriots and a young Arizona Cardinals team the next two weeks. The 49ers should be able ...

It's the season of the running back, so far. And two unlikely candidates stand on the brink of joining an elite club.Per the ...

Bill Speros writes: "SoFi Stadium has become home turf for the 49ers. San Francisco is playing for keeps this season and desperately needs an NFC West win here. The 49ers covered 66% of the time ...

The San Francisco 49ers have one of the most well-built rosters in football. San Francisco made a run to the Super Bowl last season, although it ended up losing to the Kansas City Chiefs.

The Vikings beat San Francisco 23-17 on Sunday. Ahead of Week 2, Jefferson spoke on the 49ers' win over the Jets in the season opener. "Respectfully, I'm not Garrett Wilson," Jefferson told reporters.

San Francisco 49ers left tackle Trent Williams ... as he posted a 95.8 percent pass block win rate last season. Behind Williams, the 49ers averaged 6.05 yards per carry when rushing to the left ...