An enzyme type noted in several cancers is the family of adenosine deaminases acting on RNA (ADARs). These enzymes convert ...

Cold sore-causing HSV-1 doesn't just hijack cells it reconfigures the entire architecture of our DNA to aid its invasion.

When proteins are made in a cell, they start out as strings of amino acids, which have to be folded into the correct, 3D ...

Investigating how mutations in tumors alter DNA’s 3D structure—and subsequently, regulatory sequences called enhancers—can ...

The latest version of Google DeepMind and Isomorphic Labs’ AlphaFold model can predict the structure and relationships not only of proteins, but “all of life’s molecules”, according to its ...

In the world of viral research, uncovering a virus’s weaknesses is often a painstaking process that requires years of ...

The malaria parasite exports an array of proteins while it resides in the erythrocytes of its host. This Review describes the functions of parasite proteins that interact with the erythrocyte ...

The principles underpinning SBDD. The starting point for all structure-based design work, whether ligand- or protein-based, is the choice of a suitable target.

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