The 49ers' biggest issue was something that's plagued them all season: They had six trips to the red zone and scored just one ...

The San Francisco 49ers have been practicing in temperatures exceeding 90 degrees this week. Sunday's game against the ...

Another fourth-quarter collapse led to another San Francisco 49ers’ loss against an NFC West rival on Sunday. Two weeks after ...

Why San Francisco 49ers changed their uniform for NFL Week 5 game against Arizona Cardinals Sunday, and why it's not the uniform they wanted to wear.

The San Francisco 49ers will wear alternate throwback uniforms that feature white pants to prepare for projected record-breaking temperatures during ...

The 49ers will have more than one opponent Sunday at Levi's Stadium, as their clash with the Arizona Cardinals also will ...

Four former San Francisco 49ers are among the 16 players in their first year of eligibility for the Pro Football Hall of Fame’s Class of 2025. Offensive tackle Joe Staley, tight ends Vernon ...

The San Francisco 49ers ruled out superstar running back Christian McCaffrey for the second consecutive week because of lingering calf and Achilles issues. Niners coach Kyle Shanahan said the ...

Biff Poggi, former hedge-fund manager turned head football coach, understands the risks and rewards of playing the stock market. Under his leadership the Charlotte 49ers bought stock in an SEC ...

Sam Howell and more had to say following the 49ers 27-10 win. See what Kyle Shanahan, Brock Purdy, Fred Warner, John Harbaugh, Lamar Jackson and more had to say following "Monday Night Football." ...

Brock Purdy and the San Francisco 49ers took on Aaron Rodgers and the New York Jets on Monday Night Football in their season opener at Levi’s Stadium as they seek to return to the Super Bowl.