An Aussie had a career day, and the rookie throwers are starting to make their mark as the NFL reached week five.

The San Francisco 49ers were thought to be among the favorites to represent the NFC in the Super Bowl for a second straight year, but they haven't ...

After swapping his cleats for a microphone, the spotlight during Sunday's game between the San Francisco 49ers and Arizona ...

The NFL denied the San Francisco 49ers' request to change to an all-white uniform set before the hottest game in Levi's ...

This was easily Purdy's worst fantasy game through weeks, but fantasy managers shouldn't panic about their quarterback the way 49ers' fans are panicking about their team's Super Bowl hopes.

The Arizona Cardinals and San Francisco 49ers play in Week 5 Sunday afternoon at Levi's Stadium with a 1:05 p.m. Arizona time ...

SportsLine's model simulated Arizona Cardinals vs. San Francisco 49ers 10,000 times and made its Week 5 NFL picks, ...

The only game in Week 5 between teams with winning records, this matchup is the "Stefon Diggs Bowl," as the Texans’ wideout plays his former team for the first time. An NFL All-Pro four consecutive ...