Two weeks after faltering on the road to the Los Angeles Rams, the 49ers blew another 10-point lead and exited with a 24-23 ...

The Arizona Cardinals and San Francisco 49ers play in Week 5 Sunday afternoon at Levi's Stadium with a 1:05 p.m. Arizona time ...

Prove you are the No.1 San Francisco 49ers fan with this San Francisco 49ers #16 Joe Montana Scarlet Retired Player Game Jersey from Nike! Celebrate the accomplishments and undeniable legacy of Joe ...

On a single play, the San Francisco 49ers were victims of not one but two impressive feats of downfield athletic prowess from guys wearing different uniforms. An NFL official went viral Sunday ...

San Francisco 49ers star tight end George Kittle was carted off the field against the Minnesota Vikings. The good news is that Kittle just needed an IV because he was cramping. George Kittle #85 ...

The San Francisco 49ers picked up their first loss of the season, falling 23-17 to the Minnesota Vikings in Week 2. A special teams error, two turnovers (interception and fumble) and two turnovers ...

The Minnesota Vikings will host the San Francisco 49ers this Sunday at U.S. Bank Stadium in Minneapolis for week two of the NFL's regular season. Kickoff is scheduled for 1 p.m. ET and the game ...

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The San Francisco 49ers will be without star running back Christian McCaffrey for a while. The 49ers are placing McCaffrey on injured reserve, a person familiar with the situation told USA TODAY ...

LATEST Sept. 14, 10:30 a.m. The San Francisco 49ers are placing Christian McCaffrey on injured reserve on Saturday, according to multiple reports. ESPN’s Adam Schefter and NFL Network’s Ian ...

San Francisco 49ers star running back Christian McCaffrey is set to miss his second straight game to start the 2024 season. Per ESPN's Adam Schefter, the 49ers ruled out McCaffrey for Sunday's ...