INGLEWOOD, Calif. – The San Francisco 49ers looked like they were going to cruise to their first NFC West win in front of a sea of red and gold at SoFi Stadium. San Francisco jumped out to a 14 ...

SAMUEL: "In my eyes, we've been the best team in the league for a while." TRANSLATION: The 49ers don't have to do anything different to get over the hump because they're already over the hump.

Fred Warner had some pointed and honest comments for his 49ers teammates after a frustrating 23-17 loss to the Minnesota Vikings on Sunday at U.S. Bank Stadium. Speaking to the assembled media ...

The start of the NFL season has been littered with injuries, and the San Francisco 49ers have not escaped the outbreak. With star running back Christian McCaffrey already on injured reserve ...

Jennings (ankle) had two receptions (on four targets) for 37 yards in Sunday's 23-17 loss to Minnesota. Jennings carried a questionable tag through the practice week after picking up an ankle ...

The San Francisco 49ers weren't surprised by his success in the 23-17 victory by the Vikings on Sunday, but they sure were kicking themselves for some of his opportunities. "It hurts my soul ...

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MINNEAPOLIS -- The San Francisco 49ers placed star running back Christian McCaffrey on injured reserve with calf soreness and Achilles tendinitis, the team announced Saturday. McCaffrey must miss ...

Christian McCaffrey was a surprise inactive in the San Francisco 49ers’ first game of the season last week, and it sounds like the star running back could sit out Week 2 as well. During a Friday ...

LATEST Sept. 14, 10:30 a.m. The San Francisco 49ers are placing Christian McCaffrey on injured reserve on Saturday, according to multiple reports. ESPN’s Adam Schefter and NFL Network’s Ian ...

San Francisco 49ers star running back Christian McCaffrey is set to miss his second straight game to start the 2024 season. Per ESPN's Adam Schefter, the 49ers ruled out McCaffrey for Sunday's ...