The NFL denied the San Francisco 49ers' request to change to an all-white uniform set before the hottest game in Levi's ...

The Arizona Cardinals and San Francisco 49ers play in Week 5 Sunday afternoon at Levi's Stadium with a 1:05 p.m. Arizona time ...

There is a slight chance that Fred Warner and George Kittle aren't available for the 49ers against the Cardinals ... is committed to ensuring he delivers transparent analysis and straightforward ...

The San Francisco 49ers will wear alternate throwback uniforms that feature white pants to prepare for projected record-breaking temperatures during the team's Week 5 matchup with the Arizona ...

The San Francisco 49ers have begun to turn the page to their ... Sanchez is committed to ensuring he delivers transparent analysis and straightforward opinions that resonates with readers to ...

The following player has been promoted to the active roster from the team's practice squad: The 49ers announced that TE George Kittle has been ruled out for the team's Week 3 matchup vs.

"I had a conversation with Rhamondre and, quite frankly, this week he won't be starting," Mayo told host Scott Zolak. "I'll ...

San Francisco 49ers head coach Kyle Shanahan addressed running back Christian McCaffrey's bilateral Achilles tendonitis for the first time, following comments made by general manager John Lynch.

The San Francisco 49ers will be without star running back Christian McCaffrey for a while. The 49ers are placing McCaffrey on injured reserve, a person familiar with the situation told USA TODAY ...

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As the San Francisco 49ers gear up for another run at a Super Bowl title, they find themselves with some unexpected holes to fill. All season, the 49ers' roster has been decimated by injuries ...