The NFL denied the San Francisco 49ers' request to change to an all-white uniform set before the hottest game in Levi's ...

The Arizona Cardinals and San Francisco 49ers play in Week 5 Sunday afternoon at Levi's Stadium with a 1:05 p.m. Arizona time ...

It's awfully early in the 2024 season still, but the San Francisco 49ers already have a sense of urgency. The 49ers lost to the Minnesota Vikings on Sunday, but they've also been losing key ...

The San Francisco 49ers are loaded with plenty of top-tier talent but may not be able to keep the entire core together. San Francisco entered the season among the top contenders to win the Super ...

San Francisco 49ers star tight end George Kittle was carted off the field against the Minnesota Vikings. The good news is that Kittle just needed an IV because he was cramping. George Kittle #85 ...

The San Francisco 49ers picked up their first loss of the season, falling 23-17 to the Minnesota Vikings in Week 2. A special teams error, two turnovers (interception and fumble) and two turnovers ...

The Minnesota Vikings will host the San Francisco 49ers this Sunday at U.S. Bank Stadium in Minneapolis for week two of the NFL's regular season. Kickoff is scheduled for 1 p.m. ET and the game ...

MINNEAPOLIS -- The San Francisco 49ers placed star running back Christian McCaffrey on injured reserve with calf soreness and Achilles tendinitis, the team announced Saturday. McCaffrey must miss ...

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The San Francisco 49ers will be without star running back Christian McCaffrey for a while. The 49ers are placing McCaffrey on injured reserve, a person familiar with the situation told USA TODAY ...