The Madden Curse has once again cast its shadow, this time over San Francisco 49ers superstar Christian McCaffrey (CMC).

The NFL denied the San Francisco 49ers' request to change to an all-white uniform set before the hottest game in Levi's ...

The Arizona Cardinals and San Francisco 49ers play in Week 5 Sunday afternoon at Levi's Stadium with a 1:05 p.m. Arizona time ...

The New England Patriots and San Francisco 49ers play on Sunday, Sept. 29, at Levi's Stadium in a game on the NFL Week 4 schedule. Which team will win the Week 4 NFL game? The 49ers are a 10.5 ...

It's awfully early in the 2024 season still, but the San Francisco 49ers already have a sense of urgency. The 49ers lost to the Minnesota Vikings on Sunday, but they've also been losing key ...

The San Francisco 49ers are loaded with plenty of top-tier talent but may not be able to keep the entire core together. San Francisco entered the season among the top contenders to win the Super ...

Minnesota Vikings wide receiver Justin Jefferson's 97-yard touchdown reception in the Vikings' 23-17 win over the San Francisco 49ers was the longest scoring play of Week 2 through Sunday.

San Francisco 49ers star tight end George Kittle was carted off the field against the Minnesota Vikings. The good news is that Kittle just needed an IV because he was cramping. George Kittle #85 ...

The San Francisco 49ers picked up their first loss of the season, falling 23-17 to the Minnesota Vikings in Week 2. A special teams error, two turnovers (interception and fumble) and two turnovers ...

To describe the San Francisco 49ers’ 23-17 loss against the Minnesota Vikings on Sunday as a comedy of errors would be an understatement. After a dominant performance where they played like the ...

MINNEAPOLIS -- The San Francisco 49ers placed star running back Christian McCaffrey on injured reserve with calf soreness and Achilles tendinitis, the team announced Saturday. McCaffrey must miss ...