Two weeks after faltering on the road to the Los Angeles Rams, the 49ers blew another 10-point lead and exited with a 24-23 ...

Two weeks after faltering on the road to the Los Angeles Rams, the 49ers blew another 10-point lead and exited with a 24-23 ...

The 49ers' biggest issue was something that's plagued them all season: They had six trips to the red zone and scored just one ...

The NFL denied the San Francisco 49ers' request to change to an all-white uniform set before the hottest game in Levi's ...

Nine teams scored 30-plus points and three games combined for 60 or more. Captain Kirk Cousins threw for a whopping 509 ...

The defense wilted in the heat, the offense couldn’t finish drives or protect the ball and the San Francisco 49ers blew another late lead to a division opponent in frustrating fashion.

The Madden Curse has once again cast its shadow, this time over San Francisco 49ers superstar Christian McCaffrey (CMC).

There are many ways for the San Francisco 49ers to defeat the Arizona Cardinals. But there is one way that is the most beneficial to them. The 49ers have to establish an early lead against Arizona.

The 49ers called their win over the Patriots this past Sunday a work of art. Was it really, though? NFL.com's Eric Edholm wasn't impressed. That's why he placed the 49ers 12th in his Week 5 power ...

The San Francisco 49ers will honor legends of the past and highlight Pro Football Hall of Famer Patrick Willis in their Week 5 contest against the Arizona Cardinals.

With record heat descending on the Bay Area on Sunday, the NFL has denied the San Francisco 49ers' request to wear white uniforms for their home match against the Arizona Cardinals. The decision ...