Comprehensive phosphoproteomic analysis of small populations of cells remains a daunting task due primarily to the insufficient MS signal intensity from low concentrations of enriched phosphopeptides.

Paul E. Marik, MD, FCCM, FCCP Disclosures Transfusion Alter Transfusion Med. 2010;11 (3):102-112.

Doron Aronson Disclosures Expert Rev Cardiovasc Ther. 2012;10 (2):177-189.

Background Conditions characterised by chronic visceral pain represent a significant healthcare burden with limited treatment options. While animal models have provided insights into potential ...

Vagal and spinal afferents represent the information superhighways that convey sensory information from the gut to the central nervous system. These afferents are sensitive to both mechanical and ...

Penetrating arterioles and large numbers of putative capillaries (5–10 μm in diameter) in these layers were richly endowed with immunopositive axons stained for the dopamine transporter (Fig. 1).

The mechanisms underlying the progression of diabetes mellitus and heart failure are closely intertwined, such that worsening of one condition is frequently accompanied by worsening of the other; the ...

Afferent arterioles, preconstricted with 0.5 μmol/L norepinephrine, averaged 18±1 μm (n=25) at a renal perfusion pressure of 100 mm Hg. Superfusion with 0.01 to 100 nmol/L of the 11,12-EET analog ...

The spleen is a key site for extramedullary hematopoiesis that hosts a rare population of functional hematopoietic stem cells (HSCs). While the microenvironment that supports extramedullary ...