The thrombolytic protocol was approved by the institutional review board. Alteplase (Activase, Genentech) was prepared in 1-mL portions at a concentration of 1 mg/mL from 50-mg alteplase vials in ...

Compared to alteplase, the authors noted ... improving neurologic function after ischemic stroke. It's unlikely that Genentech -- the manufacturer of both drugs -- will seek approval for this ...

Since the removal of urokinase (Abbokinase, Abbott Labs, Abbott Park, IL) from the US market, either recombinant tissue plasminogen activator (rt-PA) (Alteplase, Genentech, South San Francisco ...