Though the renal protection provided by antihypertensive doses of ACE inhibitors and ARBs has been extensively studied, the dose response of these agents may be different for renal protection.

High-dose angiotensin-converting-enzyme inhibitors, however, are at least as effective as high-dose angiotensin blockers and less expensive. Angiotensin-converting-enzyme inhibition is thus the ...

[16] Postinfarction, ACE inhibitors and ß and blockers improve ... The OPtimal Trial In Myocardial Infarction with the Angiotensin II Antagonist Losartan (OPTIMAAL) randomized 5477 patients ...