There are very few effective treatments to slow the symptoms of amyotrophic lateral sclerosis, also known as motor neurone ...

Distribution of Ranvier nodes along myelinated axons is a critical determinant of conduction velocity, significantly influencing spike arrival timing and hence neural circuit function. The patterns of ...

The data convincingly show that the transcription factor Sp1 regulates ephrin-mediated axon guidance in the spinal cord. Although the authors show that Sp1 and its co-activators p300 and CBP are ...

Purpose: The pharmacology, pharmacokinetics, clinical efficacy, and safety of rasagiline are reviewed. Summary: Rasagiline is a novel, investigational propargylamine that irreversibly and ...

Levels of iNOS in the CNS are low, but iNOS can be induced in astrocytes or microglial cells following events such as inflammation, viral infection or trauma 12,19. Neuronal NOS is localized in ...