Epstein-Barr virus reprograms autoreactive B cells, possibly contributing to systemic lupus erythematosus, with infected B cells in patients showing high antigen-presenting capabilities.
Researchers identified a key receptor that primes the formation of autoreactive B cells. Disrupting this pathway may be a potential therapy for lupus and beyond.
Spinal Cord Injury (SCI) is a devastating neurological disorder that often leads to permanent neural dysfunction. Current ...
This study provides valuable data on the role of Hsd17b7, a gene involved in cholesterol biosynthesis, as a potential regulator of mechanosensory hair cell function. The authors used both zebrafish ...
Dynein-2 is a motor protein essential for retrograde intraflagellar transport (IFT) on the A-tubule of ciliary doublet ...
Multi-omics analyses reveal redundant functions of yeast mRNA decapping activators Scd6 and Edc3 in facilitating recruitment of helicase Dhh1 and accelerating degradation of transcripts required for ...
Background Chronic stress is a known risk factor for cancer metastasis. However, the underlying mechanisms, particularly ...
Background Eosinophilic oesophagitis (EoE) is a chronic allergic disease characterised by oesophageal epithelial remodelling, barrier dysfunction and inflammation. The transcription factor forkhead ...