To investigate the hypocholesterolemic mechanism of barley in vivo, six-week-old C57BL/6J mice were fed a high-fat diet (HFD) or high-fat diet containing barley (HFD-B) for seven weeks. Total and LDL ...

Extruded breakfast cereals (EBC), processed from two oat lines, N979-5-2-4 (N979) and “Jim”, with β-glucan concentrations of 8.7 and 4.9%, respectively, were used to determine the impact of dry solids ...

Because it fosters our dreams of immortality, regeneration has been for centuries a matter of fascination for countless biologists and clinicians. While in mammals regeneration is obviously less ...

Cholestasis of pregnancy can be very uncomfortable and may increase the risk of complications for both the mother and the ...

Bile acids (BAs) have traditionally been viewed as mere ‘detergent’ molecules responsible for absorption of dietary fats and lipid-soluble vitamins. However, over the past decade, research in the ...

Background: Barrett’s oesophagus is a premalignant condition associated with an increased risk for the development of oesophageal adenocarcinoma (ADCA). Previous studies indicated that oxidative ...

In addition, hepatocyte bile acid storage protein is absent from Tcf1−/− mice. ... secreted proteins and transcription factors, were differentially expressed (Table 1; see also Web Table A).

Bile acids (BAs) are critical mediators of metabolic and immune regulation, influencing both liver ... Zheng M, Zhou J, Gong H, et al. Bile acid-dependent transcription factors and chromatin ...

In a new study, researchers explored quantifying bile acids and tryptophan metabolites in human serum samples was created using ultrahigh-performance liquid chromatography coupled with tandem mass ...