Research led by the Department of General and Visceral Surgery, Faculty of Medicine, University of Freiburg, Germany has ...

Now scientists have shown that bacteria in the gut microbiome can alter bile acids that are made from cholesterol; the microbes can transform these bile acids into metabolites that help the immune ...

Poor solubility and bioavailability are becoming increasingly problematic for drug developers as more complex molecules are entering the development pipeline. “Bile acids are nature’s surfactants, ...

In a paper in Nature, researchers at the Chinese Academy of Sciences and Xiamen University report that they have identified one such caloric restriction mimetic—a bile acid called lithocholic ...

Bile acids are essential to digestion, by acting like a kind of detergent that breaks up fat molecules. Fat doesn't dissolve in water, but our digestive system is full of water, so the fat we consume ...

Summary In the realm of biological sciences, bile acids stand as pivotal molecules, playing a multifaceted role in various physiological processes within organisms. Bile acids are specialized ...

Roger Viney, chief commercial officer at ICE Pharma, sat down with Grant Playter, associate editor, to discuss the history and current use of bile acid therapeutics. Pharmaceutical Technology: Can you ...

Bile acids are far from ready to be used as treatment in people. But we believe that the key to preventing multiple sclerosis may be inside us already.

Cholesterol and bile acids (BAs) have been classically connected in a simple model in which cholesterol is the biosynthetic precursor of BAs and BAs are participants in intestinal cholesterol ...