Notably, bisphosphonates bind to hydroxyapatite in bone, where they are incorporated into the mineral matrix. Release of the drug from the bone mineral matrix requires bone resorption, and ...

When mice implanted with metastasis-prone human cancer cells were treated with compounds that targeted ACBP’s activity, none ...

Bisphosphonates are synthetic analogs of pyrophosphate that deposit on the surface of bone, where they are phagocytosed by osteoclasts and have an antiresorptive effect. This class of drug has a ...

Astronauts face severe health risks on their journey to Mars, dealing with muscle loss, vision changes, and immune system ...

Coffee may affect how a medication is absorbed, metabolized or removed from the body. An expert shares the seven drugs, like ...

anabolic agents should be given as initial treatment because BMD gains are larger compared with transitioning from a bisphosphonate or denosumab to anabolic medication,” Cosman said. The ...

The market is dominated by the bisphosphonates Fosamax, Actonel, Bonviva and Fosamax Plus D, which account for over 70% of the sales. The only drug outside the bisphosphonate class achieving ...

For many people, coffee is a cherished part of their morning routine, offering a needed caffeine boost and even some health ...

Between experiencing white-coat intimidation and having limited time for your appointment, it’s easy to feel flustered at ...

With more and more people signing up for weight loss drugs, the potential side effects are starting to attract attention.