This valuable study presents a novel approach to enhance the therapeutic potential of mesenchymal stromal cells (MSCs) by genetically modifying their glycogen synthesis pathway, resulting in increased ...

Hamster CCK-8 is composed of eight amino acid residues which are highly conserved among other species. Following accurate identification and characterization of hamster CCK-8, we have developed a ...

Using quantitative proteomics, the authors uncover that ZMAT3 knockout leads to upregulation of HKDC1, a gene linked to mitochondrial respiration, and that ZMAT3 suppresses HKDC1 expression by ...

Drug discovery can be a long and complex process. Medicines for neurodegenerative diseases like Alzheimer's disease are among ...

The cytotoxicity of celastrol was assessed by the CCK-8 assay. Cells were seeded in a 96-well culture plate with a density of 4000 cells per well and treated with celastrol for 72 h. After that, the ...