BMPER attenuated PI3K/AKT signaling and suppressed BMP4-driven smooth muscle activation in models of PAH. BMPER overexpression mitigated the vascular remodeling that characterizes pulmonary arterial ...

Using quantitative proteomics, the authors uncover that ZMAT3 knockout leads to upregulation of HKDC1, a gene linked to mitochondrial respiration, and that ZMAT3 suppresses HKDC1 expression by ...

This valuable study presents a novel approach to enhance the therapeutic potential of mesenchymal stromal cells (MSCs) by genetically modifying their glycogen synthesis pathway, resulting in increased ...

CHICAGO — A 14-gene molecular assay could help predict which patients with early-stage non-small cell lung cancer will benefit from adjuvant chemotherapy, according to results of the AIM HIGH ...

The mitochondria play a crucial multifunctional role in the progression of malignant tumors. Therefore, researchers are working to understand the link between mitochondrial DNA mutations and ...