The human brain is known to contain a wide range of cell types, which have different roles and functions. The processes via ...

Implications for drug development and the FDA Traditional drug development is an extensive, expensive process focused on optimizing chemical compounds for passive diffusion into a cell by considering ...

Just a few weeks after conception, stem cells are already orchestrating the future structure of the human brain. A new ...

PROF. E. B. WILSON is the leading figure among the older American biologists—a rare combination of the scholarly mind with the adventurous research spirit. All who know him, whether personally ...

One mechanism for generating cellular diversity during development is to segregate cell-fate determinants predominantly into one daughter cell upon division. This review emphasizes the molecular ...

Most drug development focuses on tweaking molecules to improve their ability to slip through cell membranes by passive diffusion. But the new strategy takes a different path: using cell surface ...

Overcoming barriers for drug development Small-molecule drugs have been limited due to the belief that the primary mechanism of cell entry was passive diffusion, or not actively driven.

Duke University School of Medicine Most drug development focuses on tweaking molecules to improve their ability to slip through cell membranes by passive diffusion. But the new strategy takes a ...

The goal of the Stem Cell program is to conduct rigorous scientific studies to enhance our knowledge of normal and altered stem cell development and to advance treatments and improve outcomes for ...