The acquisition of Enci Therapeutics will advance Innova Therapeutics' lead program, IVT-8086, a humanized monoclonal ...

Three posters highlight advances in inflammasome inhibition, astrocyte neurotoxicity, and myelination models supporting ...

Research shows polystyrene nanoplastics accelerate ovarian cancer growth by activating CDK4/6 pathways, with Palbociclib ...

Background Eosinophilic oesophagitis (EoE) is a chronic allergic disease characterised by oesophageal epithelial remodelling, barrier dysfunction and inflammation. The transcription factor forkhead ...

Bud dormancy allows perennial plants to survive winter, but insufficient winter chill under warming climates disrupts this ...

Membrane depolarization promotes extracellular signal-regulated kinase activation and cell proliferation via phosphatidylserine dynamics.

Approved JAK inhibitors such as ruxolitinib and fedratinib target the JH1 kinase domain, offering symptomatic relief but lacking selectivity for the mutant form. This non-selective inhibition disrupts ...

Background: Acute myeloid leukemia (AML) remains a clinical challenge with suboptimal long-term survival. While circular RNAs derived from the RNF220 host gene have been implicated in AML pathogenesis ...

Introduction: The exhaustion of chimeric antigen receptor T cells (CAR-T) hampers the efficacy of CAR-T cell therapy. Persistent antigen stimulation in T cells results in a surge of intracellular ...