Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing ...

With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to ...

A study reveals how the essential red blood cell transcription factor KLF1 recognizes DNA. Using precise measurements in test ...

LMU scientists have shown that a fundamental process of life works differently than previously assumed. The basic process of life, known as transcription, is the process by which the genetic ...

Previously overlooked regions at the start of human genes have been shown to accumulate mutations far more often than would ...

Researchers have discovered that in thale cresses histone H3 lysine-9 (H3K9) methylation, conventionally thought to be a mark of turning off gene transcription, can also turn on gene expression via ...

The central dogma of molecular biology describes the flow of genetic information. It was first described by Francis Crick in 1956 as one-way traffic: as: "DNA makes RNA and RNA makes protein." A ...

The DNA in the cell nuclei of higher organisms is tightly coiled around protein complexes called nucleosomes, which repress gene expression. Researchers in Germany have now developed a model that ...

Genetics is the study of heritable changes in gene activity or function due to the direct alteration of the DNA sequence. Such alterations include point mutations, deletions, insertions, and ...

Figure 1: Amino acid sequence comparison of the basic regions of members from several bZIP subfamilies. Figure 2: Sequences of the Pap1 bZIP motif and its cognate DNA oligomer. The Pap1 dimer contacts ...

DNA binding specificities of transcription factors (TFs) are a key component of gene regulatory processes. Underlying mechanisms that explain the highly specific binding of TFs to their genomic target ...

Mitochondria are often described as the cell’s power plants, but a wave of new research suggests their genetic material may ...