Learn more about the research of Mayo Clinic's Gene Editing and Cellular Engineering Laboratory led by David (Chun-Wei) D.

Amber Salzman, Ph.D., CEO at Epicrispr Biotechnologies, joined the Business of Biotech live in Boston to talk about ...

This study demonstrates that Setd2 overexpression rescues bivalent gene expression during zygotic genome activation (ZGA) in ...

The research revealed widespread disruptions in the activity of genes responsible for early embryonic genome activation, metabolic processes, epigenetic regulation, and chromatin structure in embryos ...

The findings, published in Nature Cancer, identified two distinct epigenetic states that arise during development and are linked to cancer risk.

Epigenetics regulates gene expression through modifications, impacting health and disease. Aberrant patterns can lead to conditions like cancer and depression.

Scientists at the IMB have identified 5-formylcytosine (5fC) as an activating epigenetic mark that initiates gene expression in early vertebrate development. This discovery challenges previous notions ...

The researchers wanted to create an epigenetic map that followed the transition of pluripotent stem cells into specific types of neurons. The study focused on an epigenetic feature known as histone ...

They found epigenetic changes in the blood of a group of 540 people without the disease and they linked this to the future development of type 2 diabetes in half of the individuals.

In contrast, individuals whose mothers were exposed to famine later during pregnancy did not contain these epigenetic marks. This means that the specific stage of her offspring’s development during ...