While liver stiffness measurement by vibration-controlled transient elastography with a 25 kPa threshold might detect CSPH, the overall low quality of the studies means that these results are not very ...

Treg therapeutic designed to preferentially traffic towards its ligand CXCL12 over expressed in the bone marrow and spleen in myelofibrosis. -- CK0804 engages with antigen presenting cells within ...

CK0804, a regulatory T cell therapy, received FDA orphan drug designation for myelofibrosis, supporting rare disease treatment development. Clinical study results showed significant reductions in ...

July 31 -- THURSDAY, July 30 (HealthDay News) -- Though its reputation doesn't rank down there with the appendix, the spleen isn't exactly known as a vital organ. In fact, plenty of people do fine ...

Researchers have designed a microfluidic device, or 'spleen-on-a-chip,' that can model how the spleen's filters become clogged by sickled red blood cells, leading to a life-threatening condition known ...

Electrical pulses may represent a new way to treat IBD without any medications. In A Nutshell Soft wireless implant wrapping around the splenic nerve reduced gut inflammation in rats over seven weeks ...

Among previously untreated adults with Gaucher disease type 1, a genetic disease in which there is improper metabolism due to a defect in an enzyme, treatment with the drug eliglustat resulted in ...

Spleen stiffness measurement (SSM) demonstrated strong predictive accuracy for liver decompensation in patients with compensated advanced chronic liver disease (cACLD), with an optimal cutoff of 50 ...

Genetic diseases caused by mutations in single genes have long been the darling of gene therapy efforts. In a twist on this theme, a team from the Weizmann Institute of Science (Rehovot, Israel) has ...