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Scientists use AI to decode protein structures behind bitter taste detection

Receptor proteins, expressed on the cell surface or within the cell, bind to different signaling molecules, known as ligands, ...

Scientists uncover how cellular receptors trigger inflammation and sensory changes

In two new studies, scientists at Oregon Health & Science University have uncovered detailed blueprints of how certain ...
The Scientist

How Exercise Keeps the Mind Sharp Against Parkinson’s Disease

With the global rise of a “Parkinson’s Pandemic,” researchers have high hopes that prescribing exercise can slow the ...

Bipolar Disorder Treatment Pipeline Shows Strong Momentum as 20+ Pharma Companies in the Race | DelveInsight

The bipolar disorder clinical trial landscape is evolving with 25+ therapies, namely, KarXT (BMS), RAP 219 (Rapport Therapeutics), ABBV-932 (AbbVie Inc.), ABX-002 (Autobahn Therapeutics), ALTO-100 ...

Schizophrenia Pipeline 2025: FDA Updates, Therapy Innovations, and Clinical Trial Landscape Analysis by DelveInsight | Lundbeck, Intra-cellular Therapies, Sumitomo P…

In September 2025, The FDA approved an injectable extended-release risperidone suspension from Amneal Pharmaceuticals, ...
Fox News

That morning cup of coffee could be the key to a happier day, new study suggests

A recent study found that your morning cup of coffee really does make you happier – even if you're not a caffeine addict. The study involved researchers from the University of Warwick in the United ...
The Lancet

Camizestrant, a next-generation oral SERD, versus fulvestrant in post-menopausal women with oestrogen receptor-positive, HER2-negative advanced breast cancer (SERENA-2): a ...

qResearch and Early Development, Oncology R&D, AstraZeneca, Cambridge, UK rOncology Patient Safety, Oncology R&D, AstraZeneca, Cambridge, UK sLate Development ...
ahajournals.org

Soluble Triggering Receptor Expressed on Myeloid Cells 2 as a Promising Biomarker for Poststroke Depression After Acute Ischemic Stroke

Soluble triggering receptor expressed on myeloid cells 2 (sTREM2) was reported to induce inflammatory responses, enhance microglial survival, and contribute to the development of neurodegenerative ...
IEEE

Spinal Noradrenergic Alpha-2 Receptors Mediate the Antinociceptive Effects of Therapeutic Intraspinal Microstimulation

Abstract: This study investigates the role of noradrenergic signaling in the antinociceptive effects of intraspinal microstimulation intended to restore movement after spinal cord injury. Two rat ...