The specific chemosensitizing effect of Thioridazine was due to antagonism of dopamine receptor 2 (D 2 receptor; DRD2). Inhibition of D 2 receptor signaling by Thioridazine decreased MAPK and PI3K/AKT ...

Small cell lung cancer (SCLC), one of the deadliest types of lung cancer, is an aggressive tumor that metastasizes early compared to other cancers and can quickly develop resistance to chemotherapy — ...

Scientists at the University of Minnesota's Hormel Institute in Austin recently published a study that looked at a drug that ...

More information: Juan Enriquez-Traba et al, Dissociable control of motivation and reinforcement by distinct ventral striatal dopamine receptors, Nature Neuroscience (2024). DOI: 10.1038/s41593 ...

New research has overturned decades of belief about how dopamine communicates in the brain, showing it acts with pinpoint precision rather than broad diffusion.

Access free, up-to-date clinical references on dopamine receptor agonists at Healio. We aid in making confident point-of-care decisions for type 2 diabetes.

Watching other people tuck into tasty food may trigger overeating, suggests new research. Seeing others enjoying a good feed ...

Reference: Mayer FP, Stewart A, Varman DR, et al. Kappa opioid receptor antagonism restores phosphorylation, trafficking and behavior induced by a disease-associated dopamine transporter variant. Mol ...

Some autoimmune diseases are different in women and men. A group of researchers from the Chinese Academy of Sciences (CAS) has found a strong female bias in the response of a neurotransmitter receptor ...